In New York City, the 1st confirmed COVID-19 cases arose mostly through untracked transmission of the virus from Europe and various other parts of the United Claims, a fresh molecular epidemiology study of 84 patients reports. The results provide limited evidence to support any direct introductions of the disease from China, where SARS-CoV-2 originated.
The first SARS-CoV-2 case in New York State was identified in New York City by 29 February. Knowing the route it took to arrive is certainly essential for evaluating and developing effective containment strategies. Ana H. Gonzalez-Reiche and colleagues required advantage of SARS-CoV-2 sequences collected at the Position Sinai Health System through March 18, from individuals symbolizing 21 New York Town communities and two towns in neighboring Westchester Region.
The authors sequenced 90 SARS-CoV-2 genomes from 84 of the over 800 confirmed COVID-19 positive cases and analyzed these sequences together with all publicly available SARS-CoV-2 genomes from around the world (more than 2,000). The outcomes indicate SARS-CoV-2 was introduced to New York City through multiple indie but separated introductions primarily from Europe and other parts of the United Areas. Most of these instances appear connected with untracked transmission and potential travel-related exposures, the authors say.
Very few of the cases were infected with a virus that looked to be introduced from Asia, and in those, the virus was most closely related to viral isolates from Seattle, Washington. The writers also found proof that early spread of the pathogen in New York City was sustained by community transmitting. Their data also point to the limited efficacy of travel restrictions in a place once multiple introductions of the trojan and community-driven transmission possess already occurred. The results also underscore the need for early and continued broad testing to determine untracked transmitting clusters in towns.